Background and Objective: This study evaluated English for the Students of Medicine (II) (ESM) (Tahririan and Mehrabi, 2007) as one of the textbooks used for teaching English to the Iranian students of medicine. This research was performed on the basis of a number of medical students' needs analysis studying at an Iranian Medical Sciences University and one English language teacher viewpoints. It intended to identify the specific needs of medical students in a learning context and investigate whether the textbook addressed those needs.

Materials and Method: Students' profile and needs analysis forms were used to identify the language needs of 50 students as well as a teacher textbook evaluation questionnaire to elicit the teacher's attitudes towards some aspects of the textbook. The data was subjected to descriptive statistics and inferential statistics analysis.

Results: The results of the students' needs analysis indicated that English for the Students of Medicine (II) did not completely meet the students' specific needs regarding language level, some of the language skills, sub-skills, preferred learning styles, preferred type of interaction, preferred type of language, and communicative activities.

Conclusion: Based on the results of the study, we recommend authorities to replace English for students of Medicine with a more attractive textbook to meet the needs of the students of medicine and allied fields.