Volume 18, Issue 2 (2025)                   JMED 2025, 18(2): 86-95 | Back to browse issues page

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Tamunosiki Chinawa A, Onyia J, Ossai E, Nwokoye I, Nwankwo O, Nzeduba C et al . Clinical students' perception of acute rheumatic fever and knowledge of vaccine development in the future: A cross-sectional study among medical students in Enugu State, Nigeria. JMED 2025; 18 (2) :86-95
URL: http://edujournal.zums.ac.ir/article-1-2330-en.html
Clinical students' perception of acute rheumatic fever and knowledge of vaccine development in the future: A cross-sectional study among medical students in Enugu State, Nigeria
Awoere Tamunosiki Chinawa1 , Jude Onyia2 , Edmund Ossai3 , Ikenna Nwokoye3 , Ogonna Nwankwo4 , Chiesonu Nzeduba4 , Josephat Chinawa *5
1- Department of Community Medicine, College of medicine ESUT, Enugu, Enugu State, Nigeria
2- College of Medicine, UNN, Enugu
3- College of Medicine, FETA, Abakaliki
4- College of Medicine, ESUT, ENUGU
5- College of Medicine, UNN, Enugu , josephat.chinawa@unn.edu.ng
Abstract:   (331 Views)

Background & Objective: Acute rheumatic fever (ARF) is a major public health issue among children with increased morbidity and mortality. This study aimed to explore clinical medical students' perceptions and awareness of ARF and the potential for developing a future vaccine, as well as to document the factors associated with these views.
 Materials & Methods: This cross-sectional study was conducted in two medical schools in the Enugu metropolis from July 2024 to October 2024. The study enrolled 341 clinical medical students from two medical schools in Southeast Nigeria. Data were collected using a validated interviewer-administered questionnaire. The questionnaire included 11 variables to assess the students' ARF knowledge. The maximum obtainable mark for each respondent was 29. Knowledge of ARF vaccination was assessed using eight variables.
Results: Most respondents (93.0 %) demonstrated awareness of ARF. Just over half (50.7 %) recognized sore throat as a symptom of ARF. Fifty-one point-three per cent of respondents demonstrated good knowledge of ARF. Most respondents (86.8%) knew vaccination could be an effective preventive measure against the disease if available. Fourth-year respondents were five times less likely to possess good knowledge of ARF compared to their sixth-year counterparts, with an Adjusted Odds Ratio (AOR) of 0.2 (95% Confidence Interval [CI]: 0.1-0.5). Respondents under 25 years old were three times less likely to intend to receive the ARF vaccine compared to those 25 years old and above (AOR = 0.3; 95%, CI: 0.1-0.9).
Conclusion: A considerable number of medical students were aware of the development of the ARF vaccine. This serves as a strong call to incorporate the teaching of ARF into the curriculum at all levels of medical education.
 

Keywords: medical students, acute rheumatic fever, perception, curriculum, knowledge, medical school, vaccination.
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Article Type : Orginal Research | Subject: Medical Education
Received: 2024/11/9 | Accepted: 2025/05/21 | Published: 2025/07/13
References
1. Chinawa AT, Chinawa JM. Compendium of cardiac diseases among children presenting in tertiary institutions in southern Nigeria: a rising trend. Libyan Journal of Medicine. 2021;16(1):1966217. [DOI]
2. Chinawa JM, Eze JC, Obi I, et al. Synopsis of congenital cardiac disease among children attending university of Nigeria teaching hospital Ituku Ozalla, Enugu. BMC Research Notes. 2013;6:1-6. [DOI]
3. Chinawa JM, Obu HA, Eke CB, Eze JC. Pattern and clinical profile of children with complex cardiac anomaly at university of Nigeria teaching hospital, Ituku-Ozalla, Enugu State. Nigeria. Nigeria Journal of Clinical Practice. 2013;16(4):462-7. [DOI]
4. Josephat M. Chinawa, Fortune A. Ujunwa. Medical and social outcomes in the management of cardiac diseases in children. Common Pediatric Diseases: Current Challenges. 2023;2(1):130. [DOI]
5. Watkins DA, Johnson CO, Colquhoun SM, et al. Global, regional, and national burden of rheumatic heart disease 1990-2015. New England Journal of Medicine. 2017;377(8):713-722. [DOI]
6. Marijon E, Ou P, Celermajer DS, et al. Prevalence of rheumatic heart disease detected by echocardiographic screening. New England Journal of Medicine. 2007;357(5):470-6 [DOI]
7. Beaton A, Okello E, Lwabi P, Mondo C, McCarter R, Sable C. Echocardiography screening for rheumatic heart disease in Ugandan schoolchildren. Circulation. 2012;125(25):3127-32. [DOI]
8. Nkereuwem E, Ige OO, Yilgwan C, Jobe M, Erhart A, Bode-Thomas F. Prevalence of rheumatic heart disease in North-Central Nigeria: a school-based cross-sectional pilot study. Tropical Medicine and International Health. 2020;25(11):1408-1415. [DOI]
9. Susy Kotit, David I. W. Phillips, Ahmed Afifi, Magdi Yacoub. The “Cairo Accord”- Towards the Eradication of RHD: An Update Frontiers. Frontiers in Cardiovascular Medicine. 2021;8:690227. [DOI]
10. Nkoke C, Luchuo EB, Jingi A, Makoge, C. Rheumatic heart disease awareness in the south west region of Cameroon: a hospital based survey in a Sub-Saharan African setting. PLoS ONE. 2018;13(9): e0203864. [DOI]
11. Musuku J, Lungu JC, Machila, E et al. Epidemiology of pharyngitis as reported by Zambian school children and their families: implications for demand-side interventions to prevent rheumatic heart disease. BMC Infectious Diseases. 2017;17(1):473. [DOI]
12. Kotby AA, Habeeb NM, Ezz El Elarab S. Antistreptolysin O titer in health and disease: levels and significance. Pediatric Reports. 2012; 2;4(1): e8. [DOI]
13. Animasahun BA, Madise Wobo AD, Itiola AY, Adekunle MO, Kusimo OY, Thomas FB. The burden of rheumatic heart disease among children in Lagos: how are we fairing? Pan African Medical Journal. 2018; 29:150 [DOI]
14. Sheel M, Moreland NJ, Fraser JD, Carapetis J. Development of group A Streptococcal vaccine: an unmet global health need. Expert Review of Vaccines. 2016;15(2):227-38. [DOI]
15. Israel GD. Sampling the evidence of extension program impact. Gainesville, FL: University of Florida cooperative extension service, institute of food and agriculture sciences, EDIS; 1992. [Online]. Available from: [Accessed: Apr.12, 2025] [DOI]
16. Ray M, Guha S, Ray M, et al. A questionnaire survey for improving awareness of rheumatic heart disease among school-aged children in India. Indian Heart Journal. 2020;72(5):410-5. [DOI]
17. Zhong BL, Luo W, Li HM, et al. Knowledge, attitudes, and practices towards Covid-19 among Chinese residents during the rapid rise period of the Covid-19 outbreak: a quick online cross-sectional survey. International Journal of Biological Science. 2020;16:1745-52. [DOI]
18. Alnemari W, Bakry S, Albagami S, et al. Awareness and knowledge of rheumatic heart disease among medical students comparing to other health specialties students in Umm Al-Qura University, Makkah city, KSA: Analytic cross-sectional study. Medical Science. 2022;26(121):1-7 [DOI]
19. Nkoke C, Luchuo EB, Jingi AM, Makoge C, Hamadou B, Dzudie A. Rheumatic heart disease awareness in the South West region of Cameroon: a hospital based survey in a Sub-Saharan African setting. PLoS One. 2018;25;13(9):e0203864 [DOI]
20. Chelo D, Tasha L, Tamdja A, et al. Assessment of knowledge, attitudes and practices (KAP) on rheumatic heart disease among senior medical students in Cameroon. World Journal of Cardiovascular Disease. 2020;10(6):363-78. [DOI]
21. Fakieha AY, Zafer DO, Alkalash SH et al. Knowledge and attitude of rheumatic fever and rheumatic heart disease among the Makkah city population, Saudi Arabia. Cureus. 2024;2;16(1):e51539. [DOI]
22. Almadhi AA, Alshammri MR, Altamimi NO, et al. Rheumatic fever and rheumatic heart disease-related knowledge, attitude, and practice in Saudi Arabia. Cureus. 2021;13(11):e19997. [DOI]
23. Mougrabi MM, Aljuaid RS, Alrabie AD, Althumali NK, Alkhaldi LH, Alotaibi WD. Awareness of rheumatic fever and rheumatic heart disease among the population in Taif, Saudi Arabia 2020. Journal of Family Medicine and Primary Care. 2021;10(8):3056-63 [DOI]
24. Sayed AK, Se'eda H, Eltewacy NK, et al. Awareness of rheumatic heart disease in Egypt: a national multicenter study. Journal of Cardiovascular Development and Disease. 2021;4;8(9):108. [DOI]
25. Kulik E, Stuart B, Willcox M. Predictors of rheumatic fever in sore throat patients: a systematic review and meta-analysis. Transaction of the Royal Society of Tropical Medicine and Hygiene. 2022;4;116(4):286-297 [DOI]
26. 26. Manase M. Awareness of rheumatic heart disease prevention among primary health care providers and people age nine years and above in Kinondoni municipality. MSc. Dissertation. Dar Esalam; Tanzania. 2011. [Online]. Available from: [Accessed: Apr.12, 2025]. [DOI]
27. Carapetis JR, Beaton A, Cunningham MW, et al. Acute rheumatic fever and rheumatic heart disease. Nat Rev Dis Primers. 2016; 14;2:15084 [DOI]
28. Vaz LE, Kleinman KP, Lakoma MD, et al. Prevalence of parental misconceptions about antibiotic use. Pediatrics. 2015;136(2):221-31. [DOI]
29. María MR. Awareness of rheumatic heart disease prevention among primary health care providers and people aged nine years and above in Kinondoni municipality. Dar Esalam; Tanzania. [Online]. Available from: [Accessed: Apr.12, 2025]. [DOI]
30. Yadeta D, Hailu A, Haileamlak A, et al. Prevalence of rheumatic heart disease among school children in Ethiopia: a multisite echocardiography-based screening. International Journal of Cardiology. 2016;15; 221:260-3. [DOI]
31. Machluf Y, Chaiter Y, Farkash R, Sebbag A, Fink DL. Rheumatic fever in large cohort of adolescents in Israel. Frontiers in Medicine (Lausanne). 2020;6:328 [DOI]
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