fa آموزش Education پژوهشي اصیل Orginal Research <div style="text-align: justify;"><span style="line-height:2;"><span style="font-size:16px;"><span style="font-family:Times New Roman;"><b>Background & Objective: </b>The use of team-based learning (TBL) as one of the active learning strategies in the education of nursing students is expanding. The purpose of this study was to investigate the effect of employing the TBL method on improving the knowledge of the cardiovascular system in nursing students.<br> <b>Materials & Methods:</b> This semi-experimental study was conducted on nursing students of Hormozgan University of Medical Sciences, Hormozgan, Iran, in 2017. The students were divided into intervention (TBL method) and comparison (traditional lecture method) groups. The intervention group was taught by the TBL method, while the control group received teaching by the lecture method during three 2-hour sessions. Pre-test and post-test were administered to all students. The data were analyzed using SPSS23 software and the significance level was considered &le; 0.05.<br> <b>Results:</b> <span lang="EN-IN">The results showed a significant difference among the students in the intervention group, whose mean score of knowledge increased from 12.45&plusmn;5.22 before the test to 32.26&plusmn;4.25 after the test (P<0.001). Moreover, the comparison of the post-test mean scores in the intervention (32.26&plusmn;4.25) and control (17.33&plusmn;4.05) indicated a significant difference between the two groups (P<0.03)</span>.<br> <b>Conclusion:</b> The adoption of novel educational methods, such as TBL, in the education of nursing students can improve their knowledge.</span></span></span></div> Active learning, Education, Lecture, Knowledge, Nursing students, Team-based learning 10 16 http://edujournal.zums.ac.ir/browse.php?a_code=A-12-1890-1&slc_lang=fa&sid=1 Farzad Zareie zareiefarzad@gmail.com 5300319475328460025024 5300319475328460025024 No Department of Nursing, Boukan School of Nursing, Urmia University of Medical Sciences, Urmia, Iran. Mohammad Reza Karimirad Karimiradr@yahoo.com 5300319475328460025025 5300319475328460025025 No Department of Psychiatric Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran. Hossein Sharafi h_sharafi68@yahoo.com 5300319475328460025026 5300319475328460025026 No Department of Operation Room, School of Para Medicine, Qom University of Medical Sciences, Qom, Iran Farhad Azadmehr farhadazadmehr@yahoo.com 5300319475328460025027 5300319475328460025027 No Department of Nursing, Boukan School of Nursing, Urmia University of Medical Sciences, Urmia, Iran keyvan Mollarahimi keyvanmollarahimi@gmail.com 5300319475328460025028 5300319475328460025028 Yes Department of Nursing. Boukan School of Nursing, Urmia University of Medical Sciences, Urmia, Iran