en آموزش پزشکی Medical Education پژوهشي اصیل Orginal Research <span style="line-height:2;"><span style="font-family:Times New Roman;"><span style="font-size:16px;"><b>Background & Objective:</b> Self-medication, defined as the use of medications without a physician&#39;s prescription, is common among medical students due to their partial medical knowledge and easy access to drugs. This study aimed to evaluate the prevalence, patterns, and attitudes regarding self-medication practices among final-year undergraduate medical students.<br> <b>Materials & Methods:</b> A cross-sectional survey was conducted among 238 final-year medical students at a tertiary care teaching hospital between September and November 2024. Data were collected using a structured anonymous questionnaire. Out of these, 224 completed responses were analyzed using descriptive and analytical statistics.<br> <b>Results:</b> The study found that 83.9% of students practiced self-medication. Female students showed a significantly higher prevalence, greater awareness of Adverse Drug Reactions (ADRs), and better adherence to treatment regimens compared to males (p<0.01). Fever (86%), pain (73.9%), and cold & cough (54%) were the most common conditions treated. Antipyretics (92.5%) and analgesics (81.9%) were the most frequently used drugs. The primary source of information was internet resources (62.7%). Overall awareness of ADRs was low (26.6%); however, 78.6% of students believed that self-medication should be avoided.<br> <b>Conclusion:</b> The high prevalence of self-medication among medical students highlights the urgent need to integrate training on rational drug use into the undergraduate medical curriculum.</span></span></span><br> &nbsp; self-medication, students, medical, drug utilization 111 119 http://edujournal.zums.ac.ir/browse.php?a_code=A-12-3514-1&slc_lang=en&sid=1 Divya G Krishnan dgkindia@gmail.com 5300319475328460037195 5300319475328460037195 No Department of Pharmacology, KMCT Medical College, Kerala University of Health Sciences, Kozhikode, Kerala, India Anukesh Vasu Keloth anukeshteaching@gmail.com 5300319475328460037196 5300319475328460037196 Yes Department of Surgery, Malabar Medical College, Kerala University of Health Sciences, Kozhikode, Kerala, India Shivani Ravindren shivaneezdale@gmail.com 5300319475328460037197 0009-0009-8676-4493 No Department of Pharmacology, KMCT Medical College, Kerala University of Health Sciences, Kozhikode, Kerala, India